Table 4 Changes in neural plasticity in suicide
From: The neurobiology of suicide - A Review of post-mortem studies
| System element | Change | Location | ||
|---|---|---|---|---|
| Neurotrophic factors | Neurotrophins | BDNF level | decreased | PFC, HIP,antidepressants-free subjects |
| NT-3 level | decreased | PFC, HIP, antidepressants-free subjects | ||
| BDNF-binding receptor | TrkB receptor concentration | decreased | PFC, HIP | |
| TrkB.T1 truncated form receptor concentration | decreased | PFC | ||
| Polyamins | Putrescine levels | increased | G | |
| Spermidine levels | increased | G | ||