Table 5 HPA axis in suicide
From: The neurobiology of suicide - A Review of post-mortem studies
| System element | Change | Location | ||
|---|---|---|---|---|
| Hormones | CRH levels | increased | LC, DLPFC, FPC, VMPFC, CN | |
| decreased | DVC | |||
| POMC mRNA level | increased | aPIT | ||
| Receptors | CRH-receptors | receptor density | decreased | FC |
| CRH1-receptor mRNA level | decreased | G | CRH1-receptor mRNA level | |
| CRH1/CRH2receptor ratio | decreased | PIT | CRH1/CRH2receptor ratio | |